منابع مشابه
TaqI RFLP at D21S137.
Chromosomal Localization: The 3 polymorphic bands were mapped to chromosome 22 using a somatic cell hybrid panel. The 2.1 kb constant band mapped to chromosome lq whereas all other constant bands mapped to chromosome 20. Whereas the active gene for hTOPl is located on chromosome 20ql 1.2—13.1, two pseudogenes are on chromosomes Iq23—24 and 22qll.2-13.1 (2). The sequences of hTOPl and the two ps...
متن کاملAsp700 RFLP at the D8S45 locus.
Source/Description of Clone: Clone pALP13-8 is a single copy 750 bp EcoRV fragment, 0.9 kb 3' of exon 4, subcloned from a 6.6 kb BamHI fragment containing the complete human c-fos oncogene (FOS) (1). Polymorphisms: are detected with TaqI (A alleles) and BstNI (B alleles) (see Figure). A) TaqI: Presence of a 1.6 kb fragment or its allele, a 0.6 kb fragment. B) BstNI: Presence of an 0.85 kb fragm...
متن کاملA BstE II RFLP at the DXS153 locus.
Source/Description: cpX12 is a 1.1 kb EcoRI single-copy genomic fragment cloned into pAT153 from a pool of 100 cosmids isolated from a human/hamster somatic cell hybrid containing only the human X chromosome (1). Polymorphism: cpX12 reveals a two-allele restriction fragment length polymorphism with bands at 0.7 kb and 1.9 kb (Al) or 2.6 kb (A2) after Southern blot analysis of human genomic DNA ...
متن کاملRegulation of Plasma HDL Cholesterol and Subfraction Distribution by Genetic and Environmental Factors Associations Between the Taql B RFLP in the CETP Gene and Smoking and Obesity
This study investigated in a healthy population (n=220) the association of the Taql B restriction fragment length polymorphism (RFLP) in the cholesteryl ester transfer protein (CETP) gene with plasma high-density lipoprotein (HDL) cholesterol concentration and subfraction distribution. A raised HDL cholesterol level was found in B2B2 homozygotes (B2 cutting site absent) and was associated speci...
متن کاملPCR detection of the TAQ1 polymorphism at the CA2 locus.
In humans, at least seven isozymes of carbonic anhydrase (CA1—CA7) are known, five of which are encoded by genes on chromosomes 1 (CA6), 8 (CA1-3) and 16 (CAT) (1). We have previously described a Taql RFLP with a 50% allele frequency near the CA2 gene (2). We have now bracketed the site with PCR (3) primers to develop an STS site. The original DNA samples (2) produced the same typings (+ = Taql...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1991
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/19.14.4020